Oncolytics Biotech Inc T.ONC

Alternate Symbol(s): ONCY

Healthcare Biotechnology

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.

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Oncolytics Biotech Inc > Results clear on some things, not on others..I’m not a Dr.

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Comment by Noteableon May 25, 2023 5:51pm

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RE:RE:Results clear on some things, not on others..I’m not a Dr.

The "triplet therapy" (Cohort 3) involving the addition of an immune checkpoint inhibitor resulted in a 70.6% disease control rate at 16 weeks versus a 46.7% control rate for the placebo of paclitaxel alone (Cohort 1). And this result occured in a heavily pre-treated group of metastatic breast cancer patients.

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