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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Healthcare Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > ONCY announces Pelareorep ≥50% ORR & mPFS Improvements
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Comment by Noteableon May 26, 2023 4:13pm
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Post# 35466463

RE:RE:RE:RE:RE:RE:RE:ONCY announces Pelareorep ≥50% ORR & mPFS Improvements

RE:RE:RE:RE:RE:RE:RE:ONCY announces Pelareorep ≥50% ORR & mPFS Improvements To repeat -  along with confirming pelreorep's single agent effectiveness, Bracelet-1 is also demonstrating pelareorep synergy in combination with an immune checkpoint inhibitor as witnessed by pelareorep + ICIs ORR, PFS, and DCR in Cohort 3 at the time the study abstract was submitted on October 22, 2022 and in advance of the ASCO meeting in June 2023. 

Demonstratng pelareorep's single agent efficacy is critically important for pelareorep's synergistic combination with various immuno-oncology agents including immune checkpoint inhibitors, CAR-T therapy, bispecifics and ADCs, and small molecules PARP and CDK 4/6 inhibitors.
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