RE:RE:RE:RE:RE:RE:RE:AA and mBCSimple due diligence on your part would have answered your question.
"All participants enrolled in the trial had previously progressed on at least one hormone-based therapy with a CDK 4/6 inhibitor. "
https://www.oncolyticsbiotech.com/press-releases/detail/601/oncolytics-biotech-announces-updated-randomized-phase-2