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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by ONCInvestoron Aug 09, 2023 11:18am
214 Views
Post# 35579572

RE:Reality Check

RE:Reality CheckIt's been forgotten, but the issue (if memory serves since it's been such a long time) with IND-213 was that the principal investigators believed that the cohorts were insufficiently randomized. Hence Bracelet. 

I've been in this stock since the busted P3 for head-and-neck. Should have bailed then, but stuck around dollar-cost averaging out of FOMO. (Strangely, investing and following this stock has actually become something of a hobby for me.) From head-and-neck to metastic breast cancer to immunocology and now to pancreatic. I had actually promised myself that I would get out after Bracelet. When they released the Panc results last December (which were legitimately good), I had a sneaking suspicion that management intended for Panc to supersede MBS. Another bait for longs. 

I am now in it until the end of the year. Why? Because I actually think that there is some efficacy here. I want to see the OS data for Bracelet and the colerectral results. I do think that if this company had a shorter operating history (say, 5 years) and better management that we would be trading at multiples of the current price.

That said, there are many, many red flags: (1) lack of insider and institutional ownership, (2) inability to execute trials in a timely manner, (3) changing narratives on MOA, (4) changing trial focus. I could go on. 

 
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