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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Post by Journeytcon Aug 10, 2023 8:57pm
341 Views
Post# 35583003

My thoughts on webnar

My thoughts on webnarKey takeaways for me and correct me if wrong...
1.  Great things begin happening from here to the end of this year that will drive share price
2.  Full steam ahead on pancreatic trial phase 3.  Signoff next couple of months with pancan.  Looking at about 180 patients.   A go no go decision after 100 by as early as end of 2024.  Enrollments gotta start early 2024 I'm guessing to make this happen.
3.   Expect enrollment in breast cancer to be a little more than 6 to 9 months from now.   Per discussion around ten minute mark..... "holding off on description of patient population until the very end". I take the very end to mean submission of the Phase 3 trial design.   Approval and enrollment to follow.   I suspect patient overall survival drives the time period.  Longer delay maybe a good thing. I expect in a good way a disconnect between PFS and overall survival that strengthens Paleo as therapeutic and may still set it apart from the competition.
4.   Both 1 and 2 come with partnership and promote ONC into a phase 3 company.   This is a very big deal.  

Some set back on metastatic breast cancer for sure with ADC.  That said... Be patient, Paleo will be a huge block buster and an industry benchmark once they include  treatment of flu symptoms in trial protocols and/or use the correct immune check point inhibitor.  Did they say they were going to try another ICI or was my memory getting away on me?
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