RE:RE:RE:RE:RE:RE:RE:RE:Thoughts on pan can deal
Hello Newcoin and always good to hear from you,
As always comments will be subjective and everyone has their view and I can understand that.
All the shareholdes are outsiders and have no real idea of what is going on other than the dd that we get from our searches and from others on the boards that do quite an amazing job.
My take only,,,,,I will start with mbc
IND 213 was outstanding and set the stage for so much for the company that they were granted a fast track with a spa to support a 400 patient trial as noted in the Decemeber 5th 2017 pr almost 6 years ago.
Then came all the support trials inbetween to solidify or confirm 213 which they could have just done by running the phase 3 IMO only (as I feel they were almost talked into Bracelet with a CI by BP).
Bottom line is as shown by the most recent prospectus is that guidance is now 550 patients (which some are ok with) but onc has now stated that the landscape has changed with ADC's and they are in discussions with the fda and have said 6-9 months before they get an idea of the direction for mbc. I stated months ago that the way mbc is going that they will most likely end up waiting for os before making any determination. The prospectus also shows that only half a million is going to be spent out of the proceeds at this time for the advancement of the mbc program. It is there for all to read.
MBC is imo no longer their lead candidate but still holds promise in the overall pkg for the company.
Now the more exciting news of course is the PANC.
From the prospectus it shows over 10 million going to advance the panc trial which is huge at this stage and leads me to believe that a lot is in place or in the works and that the company knew how much they needed to raise or what would be considered their portion to advance the trial. Suggests to me that a deal (more likely Partnership) is being sought or is in the works. What I do not like about the money raise is the 5 year warrants that were attached at this stage of the game unless that is the only way that the company could obtain the money as it suggest they are in it longer term such as partnership which is good but was really hoping for the BO at this stage.
I am still of the thought that the company will need a partner for the precision trial and by getting everything in place with the proceeds from the money raise tells the potential partner that we are ready and will make this work no matter what so time to step up. Roche seems to be the most likely candidate as that is the ci that showed the promise that brought onc to this stage with the outstanding results....but we cannot discount the possibilty of the original panc trial tha surprised everyone when the doctors phoned to tell onc that patients were still coming into the office 2 years later....big shocker for sure.
Now the 90 days will be interesting and will the company announce the details at 90 or will it be sometime q4 as suggested in the quarterly cc.
As we know anything can happen and surprises always do with this company and i feel that onc knows they can wait no longer to advance pela into a phase 3 as the changing landscape keeps making it more and more difficult.
It will be full steam ahead with panc and am thinking at least a partnership by yearend if not sooner as things need to all be put in place for the trial to proceed. Luckily the precision has most of this already which is huge and all eyes will be on the startup of the trial which I was really hoping for this year but onc has stated 2024.....
I really do not want to wait another 2 years for a readout but as some suggest it is possible for an AA especially considering the unmet need for panc and if the results could come even close then there will be no looking back for the company.
I am big positive on the panc and of course all the above is imo and some may or may not agree and that is what makes the board so very interesting...
The stage is set.