RE:RE:Government's site And why not elaborating on the additional part 4 listed below? Because of additional expenses, well if the "stage gated" trial gets to that point it will be due to better earlier results potentially going from there this is definitely helpful as they will be picking among others patients who responded well to the drug. At times they have oversold the program yet despite the pessimistic view of many after the sudden stop and trashed valuation they are not even elaborating on the additional changes to the protocol which is absurd.
Upon completion of Part 3, an ad hoc interim analysis will be conducted to select at least 2 dosing arms that will offer an acceptable risk-benefit ratio for dose expansion in Part 4 with the following population:
Part 4 (basket expansion): will comprise approximately 20 patients per dose level, per selected cancer type diagnosed with histologically or cytologically confirmed cancers, where TH1902 has been studied and/or showed activity (in Parts 1 to 3), that is refractory or resistant to standard therapies, and where current therapy is not considered to be providing benefit.
jfm1330 wrote: They published the update about the trial on Linkedin, why not a press release? Anyway, on Linkedin, they state that three sites are now recruiting, Texas, Michigan and Pensylvania. CHUM in Montreal is not recruiting yet.