RE:Curious enrollment spike pre raise...Instead of focusing on the last 3 weeks why not the past 5 months ?
Since end of March, approx 20 patients added in 5 months (average 4 per month)
That is before factoring in the May meeting momentum improvement, new CRO, and at least 6 new sites.
That is also why extrapolating much prior to March (e.g. into the Covid era) is not relevent either - which I know you are famous for.
As for your "60% point" - the statistical Trial includes the Euphrates subset (around 170) so technically they will be at 81.25% (170+90)/(170+150) = 260/320
Exceeding expectations at the 80%+ mark in an Open Label "Confirmatory" Trial, under a 28 day mortality RCT (i.e with human lives at stake), will be an interesting proposition for the FDA once the nerds complete their statistical calculations.
MM