RE:Australian doctor receives mRNA vaccine for brain cancerMay 2023 - Intratumoral delivery of the engineered oncolytic virus DNX-2401 in combination with subsequent immunotherapy with pembrolizumab may be safe and effective at improving survival outcomes in patients with recurrent glioblastoma
Validated the use of DNX-2401 in combination with immune checkpoint inhibitors (keytruda) as a safe approach that potentially opens the door to other combination therapies
https://ascopost.com/news/may-2023/combined-delivery-of-dnx-2401-plus-pembrolizumab-may-be-safe-and-effective-in-patients-with-recurrent-glioblastoma/