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Palisade Bio Inc PALI

Palisade Bio, Inc. is a biopharmaceutical company focused on developing novel therapeutics for serious chronic gastrointestinal diseases. It is engaged in advancing a PALI-2108 for the treatment of IBD, including UC and CD and are researching PALI-1908. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract. UC primarily affects the colon and the rectum. CD can affect any part of the gastrointestinal tract, from the mouth to the anus. PALI-2108 is a prodrug PDE4 inhibitor that operates through a mechanism within colon tissues, targeting the key enzyme phosphodiesterase-4 (PDE4). This enzyme is pivotal in cAMP hydrolysis, and by inhibiting PDE4, intracellular cAMP levels are elevated. This elevation leads to the downregulation of inflammatory cytokines and a reduction in the expression of cell adhesion molecules. By modulating these processes, PALI-2108 prevents the local infiltration and activation of inflammatory cells in the colon tissues.


NDAQ:PALI - Post by User

Post by Chart1on Sep 29, 2023 1:46am
131 Views
Post# 35660954

Bought in to this pos

Bought in to this posThe company is a disaster. Purely a trade for me here. A postion average at 0.54 . These dummies will pump this again to raise more money. I'll be exiting when they do. All these companies follow the same disgusting pattern. When you spot them you can make some money trading. Unfortunately the masses are getting crushed along the way.
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