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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by Gbathaton Sep 30, 2023 10:17am
96 Views
Post# 35663162

RE:RE:RE:RE:RE:SEC Filings

RE:RE:RE:RE:RE:SEC FilingsABOS indicated their $200M was sufficient to get through Phase 2.

A previous post by gold trader linked to a good analysis showing that a successful Ph2 product (better than preceding products) has a $21B valuation based on the size of the ALZ therapeutic market.

So getting through Phase 2 is the real challenge.  If they do that successfully, the share price should surge and raising the last bit for Ph3 will be easy.

I think our position for raising the Phase 2 funds will be strengthened by the Phase 1 data, especially if ARIA-E is as low as they expect.  Given that a meager $20M cost half of the company, we'll need a strong Phase 1 to get that next $150-$200M without diluting 10-fold or more.  

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