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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Quentin30on Oct 23, 2023 8:44am
319 Views
Post# 35695869

RE:Not one, but two positive news items out today

RE:Not one, but two positive news items out today Canadafan, whilst news of efficacy is always welcome, it is not the news the investment community is waiting for. They want to know that ONCY has funding to see any phase III through to submission. Pre-market isn't exactly suggesting anything different.

The company as far I recall has now been claiming for around 10 years that it is in discussions with partners. But nothing ever matierializes. UNTIL they have conclusive statistical data that Pela + Combo improves on the current standard of care, the PPS is going nowhere but down as they burn through cash.

It's way beyond time for ONCYto either put up or shut up. Enough of the dog and pony show, investors want a trial, adequately financed, adequately monitored (patients with mild fever not being removed from the trials unnecessarily) and adequately powered to show statistically relevant end points.

One very positive takeaway was : A correlation between the expansion in the blood of TIL-specific clones and tumor response.

I hope that will enable some meaningful chance of an accelerated approval pathway...


But pre-market doesn't seem to value this data one jot.... so, now we wait till Q3 results call

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