RE:RE:ONCY's pelareorep enables CAR-T trafficking in solid tumorsYes and the thing I never realized at first either is CAR-T therapy is quite toxic and does destroy a lot of normal cells too, that's ok in WBC because your body is constantly making more white cells and will be replaced fairly quickly.
If you direct a CAR-T to say colon cancer, you could destroy your colon and it could be irreparable.
So you need a much more specific solution or targeting.
Pelareorep with a CAR-T attached is a perfect solution because it only infects cancer cells and will deliver the CAR-T to the cancer cell only. Cheers!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!