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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by Qwerty54321on Dec 05, 2023 11:03am
106 Views
Post# 35769042

RE:RE:RE: GLP-1 receptor agonist

RE:RE:RE: GLP-1 receptor agonist

Hindsight is great!

It was a risk/reward scenario. The expectation was one of the early drugs would get approved, that would have likely encouraged investment in that drug sector and MAYBE THTX could have gobbled up a bit of that. They took the cheapest route to position themselves as a possibility. As we saw things didn't work out that way.

If it had been me, I'd have wanted to see more patients dosed in a focused phase 2b and likely bankrupted the company. They took a cheap option to position at a slim chance of a biggish payoff and didn't get it. Not uncommon in biotech.


jfm1330 wrote: They stopped it after phase I because they were already behind many other companies, Should never have spent money on a phase I on this peptide. Wasted money, but hey, at the time they had plenty of cash and about 30 M shares outstanding.

https://go.gale.com/ps/i.do?id=GALE%7CA267769258&sid=sitemap&v=2.1&it=r&p=EAIM&sw=w&userGroupName=anon%7E7eb08b2f&aty=open-web-entry

LouisW wrote: We all know Ozempic is GLP-1 receptor agonist. Furthermore, Roche acquires Carmot which is focusing on GLP-1 receptor agonist development. Interestingly, when I look into TH’s history, I realized that one molecular in TH’s pipeline in early 2000, TH0318 which is GLP-1 agonist…….what happen to it? Why TH terminate the TH0318 development? Anyone know?



 

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