RE:OVs improve cancer immunotherapy by reprogramming TMEONCY has been using Nanostring technology to map the effect of pelareorep on the TME.
The Nanostring panels contain the 18-gene Tumor Inflammation Signature (TIS) that measures a peripherally-suppressed, adaptive immune response and has been shown to correlate with response to checkpoint inhibitors.
Nanostring uses SNP sequencing for analyzing transcriptomes of single cells and their TME
https://nanostring.com/blog/situating-single-cell-rna-seq-in-the-context-of-multiomics/