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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Healthcare Biotechnology
Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > EU approves first I/O combination
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Post by Noteableon Jan 12, 2024 9:41pm
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Post# 35824775

EU approves first I/O combination

EU approves first I/O combinationThe European Commission (EC) has approved the first frontline immuno-oncology treatment in the EU for mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) primary advanced or recurrent endometrial cancer.

GSK’s Jemperli (dostarlimab) plus carboplatin-paclitaxel chemotherapy is indicated for these patients who are suitable for systemic ttherapy. 

[ ONCY's pelareorep + immune checkpoint inhibitors + nab-paclitaxel is an I/O combination that is Phase 3 ready for several rare and orphan diseases that will before the US and EU regulators for Accelerated Approval even sooner now than before ]

Jemperli (dostarlimab) is programmed death receptor-1 (PD-1)-blocking antibody that binds to the PD-1 receptor and blocks its interaction with the PD-1 ligands PD-L1 and PD-L2, as highlighted by research subsequently published in the European Journal of Cancer in 2016.

https://www.europeanpharmaceuticalreview.com/news/189965/gsk-immuno-oncology-treatment-achieves-novel-eu-approval/
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