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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Jan 16, 2024 5:34pm
178 Views
Post# 35830059

RE:RE:RE:RE:EU approves first I/O combination

RE:RE:RE:RE:EU approves first I/O combinationAs I have repeated stated ONCY's pelareorep enhances the effectiveness of immune checkpoint inhibitors and now that Roche, Pfizer and Merck are developing subcutaneous formulations, the likely strategy is to combine pelareorep with one or all of the respective checkpoint inhibitors, (through subsequent out-licensing of pelareorep after the acquisition of ONCY), in both IV as well as with these newer SC delivery systems, which could be the proposition for multiple continuing Phase 3 confirmatory studies involving pelareorep in combination with Roche's Pfizer's, Incyte's, and/or Merck's checkpoint inhibitors. 
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