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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by palinc2000on Feb 01, 2024 2:19pm
107 Views
Post# 35857685

RE:RE:Another article about TH1902 and immunotherapy

RE:RE:Another article about TH1902 and immunotherapy

It could be both but the bigger point is that THTX is so strapped for cash and so small that it does not have the means($ and peopke) to carry the necessary extensive research and  clinical triials on this platform UNLESS some large  pharna/ biotechs get involved!!! Seems that the pre clinical studies are stil' ongoing with a small team composed of Ex Katana members  still looking for answers.
In the meantime  proof of concept  has not been reached and  the Company has not yet disclosed if humans are getting benefits from an otherwise promising pre clinical studies .....It is  overdue to pass the baton to  pharmas involved in oncology if there is a chance that it might work ..... for the benefit of patients suffering ftom the targeted  cancer types
If no pharmas show any interest then the conclusion becomes self evident
Phase 1 b results will soon be disclosed but the next step will be cannot be THTX going solo 

PWIB123 wrote: How should I interpret this?  They aren't getting the results they want on their own and are hedging toward a different path or it doesn't matter if they get good results on their own, this opens the door to many more income streams?

scarlet1967 wrote:

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355945

"This is the first evidence that TH1902 exerts its antitumor activity, in part, through modulation of the immune tumor microenvironment and that the combination of TH1902 with checkpoint inhibitors (anti-PD-L1) could lead to improved clinical outcomes."

Another preclinical study released today confirming the TH1902 combo therapy with immunotherapy will have better efficacy results. 

It seems there research is progressively exploring the combo therapy recently.




 

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