RE:A layman's thoughts on Roche and Adaptive Phase 3.I think idea for adaptive P3 came from PanCan. They had ok from FDA to run such a program.
Because Pancreatic Cancer is so brutal and spreads so fast I think they ok'd the idea of an adaptive type program with an ongoing running control arm because of the huge unmet need in Pancreatic cancer that is well on track to become the number two in cancer deaths worldwide.
I still think that Pancreatic Cancer is the ULTIMATE test to see if Pelareorep can go after metastatic cancers that spreads well beyond the Pancreas very quickly.
After all 90% of people who die of Metastatic cancers don't die from the original cancer they die from one that has spread to another organ. So with current cancer therapies only 10% of people are going to survive a Metastatic cancer long-term.