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NervGen Pharma Corp V.NGEN

Alternate Symbol(s):  NGENF

NervGen Pharma Corp. is a clinical-stage biotech company. The Company is engaged in discovery, development and commercialization of pharmaceutical products for the treatment of nervous system damage due to injury or disease. The Company is advancing its lead compound, NVG-291, for the treatment of spinal cord injury (SCI), Alzheimer’s disease (AD) and multiple sclerosis (MS). Its NVG-291 is a therapeutic peptide, which is a mimetic of the intracellular domain of protein tyrosine phosphatase, a cell surface receptor known to interact with chondroitin sulfate proteoglycans (CSPGs) and to be involved in the regulation of neuroplasticity and central nervous system repair. It has also initiated preclinical evaluation of a new development candidate, NVG-300, in models of ischemic stroke, amyotrophic lateral sclerosis (ALS) and spinal cord injury. The Company's wholly owned subsidiaries include NervGen US Inc. and NervGen Australia Pty Ltd.


TSXV:NGEN - Post by User

Post by stargazer1on Feb 07, 2024 12:35am
370 Views
Post# 35866752

We received Fast Track approval Oct. 2023, but ...

We received Fast Track approval Oct. 2023, but ...
October 23, 2023) - NervGen Pharma Corporation announced today that the U.S. Food and Drug Administration has granted Fast Track designation for its proprietary lead compound, NVG-291, in individuals with spinal cord injury. FDA's Fast Track program is designed to facilitate the development of drugs intended to treat serious conditions and fill unmet medical needs as part of the FDA's goal to get important new drugs to patients earlier. Fast Track also provides eligibility for both Priority Review, which can shorten the New Drug Development (NDA) review process, and for Accelerated Approval, which can allow for an earlier or faster approval based on a surrogate or intermediate clinical endpoint.
..........
However, in order for NervGen's drug, NVG-291, to receive early approval, it must meet its clinical endpoints. Then it will get an early review of its results (Priority Review) and if the review is favorable, it will be evaluated for Accelerated Approval.
 
Exceeding its clinical endpoints, especially if its subjects have a return of motion, even partial motion, of previously paralyzed extremities, will virtually ensure the approval of its drug NVG-291, most likely a fast approval of its drug.
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