GBM
One huge challenge with recruiting patients for NMIBC is that you are competing for patients with other studies. If you look at the number of patients treated by IBRX and CGON in relation to the number of recruitment sites it is quite the ratio. They too have a huge number of sites but the number of total patients they get is not that impressive.
When TLT gets going on GBM they won't have quite the same challenge. There is so little out there to offer GBM patients sadly. Since they are based in TO they would almost certainly do the phase 1a/b out of that city. If you look at clinicaltrials.gov the number of GBM studies being run out of Toronto are very few and most don't apply unless you have some highly specific criteria. That is why GBM patients have such a hard time, there is so little out there.
So, for future reference, when they go to GBM they may have a faster go at getting patients and results compared to NMIBC.