I was reading up on this as my good friend is going through this too. He says his is failed BCG Cis so not sure if that is close enough to what you are describing.
He lives near Toronto so his plan is to try the TLD one in that very excellent list as his urologist mentioned that it is one of the few that has some one or two and done options. As in, some people get the treatment and are effectively cured on the first treatment. Something like a third. So if he tries it and responds he doesn't have to commute repeatedly for the other drugs which are frequent bladder instillations. His master plan is to try the TLD if he can get on with the trial. Apparently if you are going to be one of those one and possibly cured long term responders you have a good chance of knowing that based on the results after 6 months. So then he thought he would ask about leaving the trial at 6 m if not responding and then joining another trial. Sounds complicated but that is his current thinking.
I got the pathology from my latest TURPT - Bladder cancer (inspire.com)