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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Feb 21, 2024 1:19pm
78 Views
Post# 35891298

RE:RE:RE:CG Oncology

RE:RE:RE:CG OncologyCG’s lead asset is an oncolytic virus immunotherapy, recently granted an Accelerated Approval for the intravesical infusion treatment of high-grade non-muscle invasive bladder cancer (NMIBC).  

With intravesical therapy, the doctor puts a liquid drug right into the patient's bladder rather than giving it by mouth or injecting it into their blood. The drug is given through a tube (urinary catheter) that's been put into the patient's bladder through their urethra.


CG Oncology's OV is an intravesically delivered oncolytic immunotherapy that was evaluated in BOND-003, a single-arm, Phase 3, monotherapy clinical trial for the treatment of patients with high-risk BCG-unresponsive NMIBC with carcinoma in situ with or without Ta/T1 disease.


https://pubmed.ncbi.nlm.nih.gov/37410243/

https://www.cancer.org/cancer/types/bladder-cancer/treating/intravesical-therapy.html

https://www.pharmexec.com/view/fda-grants-fast-track-breakthrough-designations-to-cg-oncology-inc-s-cretostimogene-grenadenorepvec
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