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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Mar 23, 2024 4:55pm
133 Views
Post# 35949020

RE:ONCY Corporate Investor Presentation

RE:ONCY Corporate Investor Presentation
Significant advantages with ONCY's pelareorep are that pelareorep is intravenously (IV) administered as opposed to intratumoral (IT) administration with other OV agents and that pelareorep is safe to use and can be manufactured at a cost efficient price point.

Furthermore, according to Wang et al. writing in the Journal for Immunotherapy for Cancer, " 
Mechanisms for intravenous delivery are being urgently sought to allow for simultaneous targeting of primary tumors and metastatic or disseminated cells which could produce a greater therapeutic effect."

As an IV delivered drug, ONCY's pelareorep meets this urgent need, and has thus resulted in a safe, effective and novel large molecule I/O biologic agent, which is eligible for 13 years of FDA market exclusivity once approved, under the IRA, in contrast to a small molecule cancer agents which only have 9 years of protection.


https://jitc.bmj.com/content/10/5/e004167
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