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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Post by canadafanon Apr 12, 2024 10:23am
177 Views
Post# 35985500

Lots of useless chatter overtop of my post/worth a repost

Lots of useless chatter overtop of my post/worth a repostIt has been a long time of silence, with anything related to upcoming phase 3. That being either the pancreatic or MBc Cancers.
In the background the science, AKA on- going trial(s) & various survivable time lines, ..have without anything that can be done, just keep on according.
As I mentioned previously, it is a troublesome paradox. The longer the patients live ( great news), the longer it takes to publicize any additional trial data.( troubling for those looking for news)
Overall survival, " results", are based on the continued lives of the patients in the trial.
Nothing to do with mangement, locations, advisors & certainly not the trading S.P.
The long awaited O.S. results are 100% based on patients health, recovery & the mortality of the cancer.
while bad for news flow, longer is better.
The most recent FDA type " C " meeting?
Some find it a requirement to point out the maximum time for an FDA response.
Considering they all ready have in- place  fast track designation. The longest time period is possible. However not likely.
depends in the complexity of the questions & expected answers.
The meetings of that calibre  usually have predetermined outcomes, Meaning a formality to validate prior discussions.
beyond that ( as we can all banter on this date or that date). a quick read if the N.R. Says quite clearly a significant briefing has been put together with the assistance of clinical collaborations & partners. & the meeting is requested for this quarter.
Meaning , soon.
Most importantly ? As was mentioned how to finance the trail,
Oncolytics biotech, has said from day one. The phase 3 & marketing of Pelareorep will require a business partner.
Since the briefing was drafted with the guidance of outside partners/ collaborators, common sense woukd be. Once a plain  in place then a proper $$ can be attributed to the costs and outcomes of that plan.
it is very possible the phase 3 environment won't start until Q3/4, of this year.
However, there will be an announced plan & partnership, long before the enrolment.
Next shoe to drop is the PanCan/ Pancreatic cancer phase 3 trial information.
Will the $$$ source be a surprise as Notable suggested?
First , I agree 100%, this meeting announcement is very good news & can lead to a modified phase 3 trial.
Second , funding a surprise?
i have stated previously, one of 3 obvious options, plus some we can't even think of.
1. A complete buyout of the company.
2. a licensing agreement with upfront $$ and biobucks based on measurable achievements.
3. A spin- off company, with ONC & the partner being co- owners.
Alternatives?
combinations of #1,2 & #3.
Other business deals?
Majority of the 6 analysts covering onc(y), have predicted a partnership announcement before the end of this year.
Using Nitables words " a surprise"
Just me, at this juncture nothing would surprise me.
The S.P. Is trading a fraction of where it should be.
Looking a bit further out, it is quite possible to get Pela to market under accelerated approval for both MBc and Pancreatic cancer.
THAT makes Onc a multi billion $$ company.
Not there yet. Obviously, however as I started.
the MBc O.S, results are taking a long time. That is great news!
not good for those in a rush, to make your quick in & out trade.
Let's see what comes next.
At least we know why the recent premarket activity.
Those who understand are buying. The others, bashing & blaming. ...it's taking too long...
BTW side note, a comment was made regarding my lack of posts on another site.
i have tried, but those moderating delete anything I post with a positive point of view 
No doubt same happening to others.
leaving that site exactly what the zfUDsters wanted a messy pile of goo.
suggesting " your" posts are deleted on this site? Not possible.
only the author can delete his/ her own posts.
exception to that, if you use outside links or inappropriate language.
regards 
wishing everyone a safe & healthy week.
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