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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Journeytcon Apr 13, 2024 1:57pm
141 Views
Post# 35987560

RE:RE:RE:RE:Type C Meeting Timings

RE:RE:RE:RE:Type C Meeting TimingsSo there it appears to be Notable.  Type C meeting about "Early consultation on use of biomarker as surrogate end point.....".     AWARE study suggested PFS of individuals with biomarker at about 70% an awesome response rate, a paradigm shift in therapeutic.    For Bracelet, we must subtract 50% from the AWARE observed PFS of 70% to determine those who can be effectively treated with Pela combination.  A large portion of patients with strongest response to Pela withdrew.   Recall symptoms of those withdrawing could have been treated effectively with Tylenol per key opinion leaders remarks. The adjusted PFS for bracelet PFS of 35% isnt very useful, and it's likely why ONC never reported biomarker stats for bracelet.    I imagine the type C meeting discussions has alot to do with this.   My apologies if I screwed this analysis.   Remarks welcomed.  
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