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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Healthcare Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > CD8+ TiLs and T-cell exhaustion
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Comment by Noteableon Apr 29, 2024 12:24pm
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Post# 36012851

RE:RE:RE:CD8+ TiLs and T-cell exhaustion

RE:RE:RE:CD8+ TiLs and T-cell exhaustionIovance Biotherapeutics is tied up in the proposed Biosecure Act. Iovance Bio received FDA approval in February 2024 for its TiLs therapy.

The Biosecure Act would prohibit U.S. companies from working with “a biotechnology company of concern” and extending any contracts, but specifically seeks to limit ties with Chinese biotechs. The proposed bill calls out a handful of companies, including Complete Genomics and WuXi AppTec, a significant biopharma partner for many U.S. drugmakers.

Biopharma startup Iovance Biotherapeutics is one U.S. company currently tied up with WuXi AppTec after its subsidiary, WuXi Advanced Therapies, was approved by the FDA in February to begin the analytical testing and manufacturing of Amtagvi, a T cell immunotherapy to treat unresectable or metastatic melanoma.

https://www.pharmavoice.com/news/lawmakers-target-chinese-biopharma-wuxi/713792/
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