Toxic oligomer hypothesis Why is it we don't get any credit for PMN310? Simple, it has been decades saying that plaque causes Alzheimer's. Now the scientific community is just starting to recognize that toxic oligomers kill neurons, not plaque. So where are we?, with 1A we show the selectivity, safety and dosage capabilities. Now with 1B we will show an increase in cognition, to what degree? If we slow and or stop neuronal death, then the world will know Promis and all our other platforms. Tick tock tick tock, soon!!!!!