RE:RE:RE:RE:RE:RE:RE:RE:RE:POC in humans has been acheived is that it
Just wanted to clarify the fact that 300mg/m2 is the higher dose level in part 3 of phase1(the second group of the patients will be dosed at that level)! Therefore what ever this new presentation will be revealing almost will be relevant as the dosage is (despite the different intervals, weekly versus previously every 3 weeks) similar to the ongoing clinical trial.
"The amended study will be a modified 6+6 design with two different dosing regimens that are within the efficacious range for sudocetaxel zendusortide: 1.75 mg/kg on days 1, 8, and 15 of a 28-day cycle (similar to 210 mg/m2 every 3 weeks) and 2.5 mg/kg on the same schedule (similar to 300 mg/m2 every 3 weeks)."
Hopefully with this more frequently dosing they will be better off in terms of both safety and efficacy of the drug.