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Eledon Pharmaceuticals Inc ELDN

Eledon Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is developing immune-modulating therapies for the management and treatment of life-threatening conditions. The Company’s lead investigational product is tegoprubart, an anti-CD40L antibody with high affinity for CD40 Ligand, a well-validated biological target within the costimulatory CD40/CD40L cellular pathway. The central role of CD40L signaling in both adaptive and innate immune cell activation and function positions it as an attractive target for non-lymphocyte depleting, immunomodulatory therapeutic intervention. Tegoprubart is engineered to potentially both improve safety and provides pharmacokinetic, pharmacodynamic, and dosing advantages. CD40L is primarily expressed on activated CD4+ T cells, platelets, and endothelial cells while the CD40 receptor is constitutively expressed on antigen-presenting cells, such as macrophages and dendritic cells, as well as B cells.


NDAQ:ELDN - Post by User

Post by whytestockson May 07, 2024 7:00pm
45 Views
Post# 36027815

Eledon Announces Clinical Progress with Tegoprubart in the P

Eledon Announces Clinical Progress with Tegoprubart in the P
News; $ELDN Eledon Announces Clinical Progress with Tegoprubart in the Prevention of Transplant RejectionFirst participant dosed in clinical trial at University of Chicago Medicine assessing the use of tegoprubart to prevent islet cell transplant rejection in patients with type 1 diabetes Company reports updated data from ongoing Phase 1b trial evaluating tegoprubart for prevention of reje...ELDN - Eledon Announces Clinical Progress with Tegoprubart in the Prevention of Transplant Rejection

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