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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Post by Journeytcon May 09, 2024 10:57am
184 Views
Post# 36031138

Todays Announcement Goblet Expansion

Todays Announcement Goblet ExpansionPure specilation on my part.  GOBLET achieved magnificent result in the GOBLET pancreatic trial with the pela ICI combo.    So why fuss with success and expand Goblet to include Folfirinix +- ICI?    High cost might limit access to treatment, limit who can be saved and reduce treatment population size.   And treatment population size affects earnings.  Pancreatic cancer is a much smaller indication tham breast and if population is further reduced on cost thats a problem.  Im guessing treatment costs would be 300,000 us dollars per patient.   150,000 dollars for pela and 150,000 dollars for ICI. 
If ONC with biomarker, can identify a large sub group within the population responding to the combo treatment, thats a big deal for patients, for cost and safety.  And i think its portends whats to come for pela in the treatment of all sorts of different cancer indications. 
Todays announcement is great especially sonce effort is sponsored by someone else.  



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