Oncolytics Biotech Inc T.ONC

Alternate Symbol(s): ONCY

Healthcare Biotechnology

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.

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Oncolytics Biotech Inc > ONCY pelareorep demonstrates 69% ORR in pancreatic cancer

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Comment by Noteableon Jun 19, 2024 1:05pm

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Post# 36096230

RE:RE:ONCY pelareorep demonstrates 69% ORR in pancreatic cancer

Of particular interestr is ONCY's pelareorep preferential infectivity on "basal-like" pancreatic cells, which is a particular characteristic in 1/10 pancreatic cancer patients in which pancreatic cancer cells appear to lose their identify and the features of pancreatic cells, and basically becoming "basal" akin to skin or espophageal or GI or breast cancer cells.

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