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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Healthcare Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > AstraZeneca's ADC disappoints - on severe adverse events
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Comment by Noteableon Jul 01, 2024 10:41am
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Post# 36113255

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:AstraZeneca's ADC disappoints - on severe adverse events

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:AstraZeneca's ADC disappoints - on severe adverse eventsJuly 01, 2024 - Gilead's antibody-drug conjugate (ADC) Trodelvy fails to reach the primary endpoint in a confirmatory Phase III trial (TROPICS-04) in patients with metastatic urothelial cancer.

Gilead reported a higher nujmber of deaths in the Trodelvy arm of the TROPICS-04 study.

Trodelvy, which is also FDA-approved for the treatment of breast cancer, earlier this year also failed a Phase III trial in non-small cell lung cancer (NSCLC), missing its overall survival endpoint. 

https://www.biospace.com/article/gilead-s-trodelvy-adc-stumbles-in-late-stage-trial-but-remains-prized-cancer-asset-/

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