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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Journeytcon Aug 02, 2024 9:28am
128 Views
Post# 36160431

RE:RE:RE:Conference Call

RE:RE:RE:Conference CallWith regard to enrollment in a phase 3 study or a transitional study that leads to a phase 3,  i think we are looking at 8 months for the pancreatic trial.  We'll know early the progression free survival results for Pancreatic disease since death from prognosis advances rapidly.   And ONC will get Accelerated Approval for this one.  Markets will see a clear timeline to a cash rainbow for pela as a pancreatic therapeutic. 

I know ONC is investigating additional treatment combinations for Pancreatic.  I assume to improve on efficacy which is outstanding, and i would think to find a less expensive solution apart from ICI combo?  Someone might want to comment on this. 

We must wait three months to hear intentions for the Breast Cancer trial design and timing.   Its definitely going to be a phase 2 with phase 3 potential in probably a few years.  Market size, timing and risk for Breast Cancer took a beating yesterday.   And speakers discussion yesterday reflected the conundrum.  

ONCs share price we all know has been totally disconnected  from the pela technology and opportunity. Even with demotion of the Breast Cancer,  ONC share price is still disconnected and perhaps now even more so.  Yesterday provided a clarity to market for Pancreatic beginning with enrollment in the near term.  ONC is dramatically under priced for this reality and the cashflows,  partnership and potential sale it brings. 
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