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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Healthcare Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > TIGIT class of checkpoint inhibitors fails with Keytruda
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Comment by Noteableon Aug 05, 2024 3:15pm
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Post# 36164908

RE:RE:RE:TIGIT class of checkpoint inhibitors fails with Keytruda

RE:RE:RE:TIGIT class of checkpoint inhibitors fails with Keytruda BMS/ Agenus TIGIT bispecific antibody BMS-986442 (AGEN1777), is a  fully human Fc-enhanced bispecific antibody, which ONCY's Phase 2 Bracelet-1 mBC demonstrated fails when the fully human Fc-enhanced region is left active in a PD-(L)1 immune checkpoint inhibitor like avelumab (Bavencio) .

https://finance.yahoo.com/news/bristol-myers-squibb-terminates-cancer-183111963.html
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