RE:RE:RE:RE:RE:RE:SO IM MISSING THE GOOD NEWSHi DJDawg - nice post. That all makes sense to me. I think it's possible the pending patients are ones for which Theralase has not yet received the post-450 day patient permission forms.
Your analysis sounds right to me. It's excitng to contemplate the possibility that 25% of all patients treated are cancer free at 3 years! Theralase will be able to claim that one quarter of all patents treated are cured of bladder cancer after 1 or 2 treatments
DJDawg wrote: The new swimmers is interesting in a few ways.
One thing that is new is that they are showing the dots and squares at the true time point date when happened. It makes sense that things never happen on the days exactly as there can be issues that arise. The explains why green dots and red squares are not a perfect line down at each time point.
Eog, I find the plot confusing in one way. The grey bars at the top represent a patient's path. The arrows are the end are indicating "ongoing response". Yet many of the grey bars have a series of Ps in them which is confusing. Pending as in there is more data needed? Pending as in we don't know if CR or NR at all. I don't think pending means that the CR status is in question since the text of the document indicates 17/41 are CR beyond 450 days. That math only works if you are counting the grey bars with P in them. So my guess is that the grey bar is CR that is known and the Pending is that they don't have the full data set (not sure why or what) on them.
So if you work off the assumption that a grey bar is CR even if it says P or green dot in particular then the numbers look very good. The one patient have disease recurrence at 810 days is very interesting and I suspect might even represent a de-novo cancer arising rather than return of the original after 27 months of being CR. Either way it is an anomaly. If you carry forward the CRs that are CR at 540 and assume all stay that way then the >3y rate will be almost 40%. If we are using the old math that would be 16/65 for a CR rate of nearly 25% at >3yrs.
Hope that makes sense and I have not erred.