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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Aug 21, 2024 12:13pm
99 Views
Post# 36190012

RE:RE:RE:RE:RE:RE:Big pharma is set to keep signing bigger deals in 2024

RE:RE:RE:RE:RE:RE:Big pharma is set to keep signing bigger deals in 2024ONCY has approximately $500 million in R&D expenses that can be transferred to ONCY's acquirer to be written off against other revenue, which benefits a Big Pharma company operating in the United States, since 100% of ONCY's costs can be written off, in contrast to US generated R&D costs. 

In 2021 the US imposed changes to the way it allows companies to deduct R&D expenses such that  now most companies must amortize those costs over 5 years. Starting in 2022, companies can no longer write off 100% of costs in the year they were incurred. Instead, to comply with these new rules, companies must amortize most of those costs over five years (15 years for R&D expenses attributed to foreign research)..

This is one of the reasons that Roche/Genentech has contributed to the company's decision to dramatically reduce its in-house R&D activites and like other Big Pharma companyies, is looking to M&A to replenish its product portfolio with new drug candidates.

Consequently the positive impact form small biotech companies are larger deal values, particuarly for late-stage clinical development companies, like ONCY, that are seeking near term Accelerated Approvals and near term market entry for their drug products..
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