RE:WHY NO INSIDER BUYERHopeforthebest believes that speculative microcap biopharma is a retirement plan and a guarentee to riches. Insiders near retirement should wildly bet it all on green he believes. The truth is that such stocks can be overwhelmed by many, many factors that have nothing to do with management. We've been in the worst biotech bear market in history. COVID and the associated interest rate and inflation shock has destroyed many biotech companies and led to catastrophic dilution. There can be economic crisis. CZO's main client was also spun-off and demand patterns suddenly changed leaving CZO at the bottom of the biotech bear market in need of cash for its next step. There can be changes in competition due to new science, etc. Demand for consumer products can also be very fickle and can be met with consumer boycotts, etc. We live in a cancel culture and companies can be seen as too woke. Jennifer Aniston recently got in a conflict with JD Vance after the childless cat lady comment. There are many scientific and regulatory risks. The diagnostic trial may not work out. PGX may take years longer to figure out. Drugs could fail. As a percentage of his overall wealth Gilles probably has too many shares. He's never sold a single share and has only added to his holdings over time. He's committed the most important professional years of his life to this company. They've invested the profits in the company's long term vision. The Canadian government has supported their plans. Pharma icon Ronnie Miller has committed his time. You need to be very well diversified given the risks here. Be humble before the many known and unkown risks or end up looking like a hyper-whiny bagholder like Hopeforthebest.