COSCIENS Biopharma Inc T.CSCI

Inflammaging: Moisturize every day...

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Based on the search results provided, there is evidence suggesting that daily moisturizing may have systemic benefits and help combat inflammaging. Here are the key points:

Moisturizing and Inflammaging

Inflammaging refers to the chronic, low-grade inflammation that occurs as we age, which is associated with various age-related diseases. Research indicates that moisturizing the skin regularly may help reduce inflammaging and provide systemic health benefits:

1. A small pilot study found that moisturizing the skin might reduce the risk of developing chronic conditions like heart disease, diabetes, and Alzheimer's disease.
2. Applying moisturizer twice daily for one month in older adults led to lower levels of inflammatory chemicals in the blood, comparable to levels seen in people in their 30s.
3. A three-year study on adults over 65 showed that those who moisturized their skin twice daily maintained their cognitive function, while the control group experienced significant decline.

Mechanism and Benefits

The potential systemic benefits of moisturizing are thought to occur through the following mechanisms:

1. Improved skin barrier function: Moisturizers help maintain the skin's integrity, reducing the entry of environmental toxins and allergens.
2. Reduced inflammation: Dry skin is associated with higher levels of inflammation. Keeping skin hydrated can help mitigate this.
3. Prevention of "inflammaging": Regular moisturizing may help prevent the chronic, low-grade inflammation associated with aging.

Recommended Practices

To potentially gain these systemic benefits:

1. Apply moisturizer at least twice daily, especially for older adults.
2. Use moisturizers containing ingredients like glycerol, petrolatum, hyaluronic acid, and skin-compatible lipids.
3. Combine moisturizing with other healthy skin practices, such as daily sunscreen use and protection from environmental stressors.

While more research is needed to fully understand the long-term systemic effects of daily moisturizing, current evidence suggests it may be a simple yet effective way to promote overall health and potentially reduce age-related decline