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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Sep 13, 2024 2:41pm
83 Views
Post# 36222824

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:ONCY pelareorep + CD3 bispecific antibody true-killer combo

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:ONCY pelareorep + CD3 bispecific antibody true-killer comboSummit Therapeutics US$19.5 Billion market cap is bizzare since their Phaswe 3 clinical trials have not been conducted in the United States and while their drug was a PD-1 + VEGF inhibitior vs. keytruda - the Phase 3 trials were not run against keytruda + the VEGF Avastin and have not reported on overall survival. So while Summitt Therapeutics may run clinical trials in the United States, Summit must begin with gaining an IND for this Chinese owned (Akeso) I/O drug combination and then run a series of clinical trials starting with Phase 1 through to Phase 3 as determined by the US FDA and not the Chinese National Medical Products Administration- all conditional on the company to report on favorable overal survival data based on keytruda + Avastin data - and not on keytruda alone, as it has in all trials reported in China.
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