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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by inthnoon Sep 15, 2024 4:40pm
66 Views
Post# 36224686

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:ONCY's pelareorep activates TiLs (CD8+ Dendritic Cells)

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:ONCY's pelareorep activates TiLs (CD8+ Dendritic Cells)
I certainly hope that you are right Note as I do not consider 3rd line patients with a compromised immune system the same patient population that was in the mbc 213 trial. As for the 55k patients, whether it will be easy to enrol or not depends upon how well we are promoted as it is still a trial and there might be a lot of companies trying for the same patients. Market has great potential but that is only if we were to capture the entire market of course (which we are hoping for panc for example) but then again that is only the potential and it would be most likely split up against competing entitities. ONC has never run a quick trial so IMO only we will be lucky if the trial even starts in 2025 as there is a lot to be approved and get into place and then enrol the patients and then wait for the first efficacy readout which is most likely sometime in 2026 if we are lucky which at this time is when the fda would look at the possibility of AA but then again only with results that warrant it. Guess we shall see but will be interesting to see how much the soon to be announced mbc os results play into things. That is the big question.
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