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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Sep 29, 2024 8:53pm
147 Views
Post# 36246324

RE:RE:RE:RE:CD8+ TiLs and T-cell exhaustion

RE:RE:RE:RE:CD8+ TiLs and T-cell exhaustionONCY has $500 million in R&D write-offs and the potential of $US 2.4 Billion in peak annual sales, according to ONCY's presentation but much higher by an estimated 2x+ more from global reports, for the 3rd line HR+/HER2- breast cancer alone that pelareorep is expectedto address, and with 13 years of FDA market exclusivity from the approval date of pelareorep.
 
And then there are 2 indications in PDAC, which would be valued at an estimated several billion dollars more, followed by anal cancer, TNBC, CRC and GI cancer indications as follow-on approvals
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