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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Dec 27, 2024 5:42pm
193 Views
Post# 36378998

RE:RE:RE:JP Morgan healthcare conference

RE:RE:RE:JP Morgan healthcare conference"  ... Every management team has their own style with the types of buyouts they prefer. Pfizer, AbbVie and BMS tend to take big bets, with much higher average deal sizes. In contrast, Lilly, Novo Nordisk and J&J tend to be much lower. With those larger $, Pfizer and BMS tend to acquire companies with more developed lead assets, usually Phase 3 or beyond. Earlier stage assets are seeing deals in the US$1-5 Billion range.

Overall, the vast majority of deals had at least a Ph2 asset. For late-stage clinical development companies with I/O oncology Ph2+ assets or later, Big Pharma's M&A "sweet spot" is in the US$5-$15 Billion range. Pharma pays up for guaranteed near-term revenue.

ONCY's is a late-stage development company with a platform technology in pelareorep that is being developed in multiple cancers with unmet medical treatment needs and is on the door-step of an near-term revenue with the grant of Breakthrough Designation (BTD) and Accerated Approval (AA) for pelareorep in breast and pancreatic cancer, either as a monotherapy or in combination with other biologics like immune checkpoint inhibitors (ICIs), bispecifics, ADCs, cell & gene (CGT)/ CAR-T therapy, and small molecules, such as CDK4, CDK6, and PARP inhibitors, for example. "


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