RE:ONCY pelareorep + CD3 bispecific antibody true-killer comboPreconditioning the tumor microenvironment with oncolytic reovirus results in the activation of immunologically cold tumors,.This in turn led to more successful engagement of bispecific antibodies, causing tumor cell death.
https://absoluteantibody.com/general/using-bispecific-antibody-reagents-to-further-research/