RE:RE:RE:RE:ARIA-EHafness wrote: aria-e would be a side effect in healthy subjects as well I would think. I pretty sure this would show up in 1-a. Aria is the number one issue with these drugs. They surely were looking for it. What am I missing.
here is a good article talking about aria
https://pmc.ncbi.nlm.nih.gov/articles/PMC3693547/
"aria-e would be a side effect in healthy subjects as well I would think."
I don't see why not!
I know from publications that before the trial begins, a baseline MRI scan is performed to establish a reference point for each healthy participant. During the trial, participants undergo MRI scans to monitor for any changes in the brain. This will detect any abnormalities, by observing ARIA at different doses.
G1945V