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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by M101on Jan 18, 2025 11:24am
99 Views
Post# 36410249

RE:RE:sage advice

RE:RE:sage adviceSage is a Boston are pharma with a CNS focused drug platform including a couple of approved depression drugs. They were in a development agreement with Biogen which is about to end, and now Biogen has made a hostile takeover bid. From Sage website:
"**Biogen terminated its rights as to the SAGE-324 program in September 2024; the termination will be effective on February 17, 2025."

So my question is about our shareholder group(s) control in such an event. I believe that there is a controlling group hiding within the list of major shareholders. It looks to me like the $2 financing price was set in stone before the 60:1 consolidation was decided, so the relevant question back then was how high a ratio was needed to gain sufficient control in all contingencies.


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