RE: Center watch clinical trialsMy understanding is that they did not do this as part of a clinical trial. What they did in the two examples was use a treatment that more closely resembled
an acticoat dressing rather than the gel that is being used in the clinical trial. The patients in the examples did not respond to any of the standard treatments
so they could probably get away with this off-label use. It should, however, be noted that the active ingredient is the same; namely nanocrystaline silver.
The information comes from the patent below.
https://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/search-bool.html&r=3&f=G&l=50&co1=AND&d=ptxt&s1=nucryst&OS=nucryst&RS=nucryst
You may also be interested in reading the two patents that were granted in April of this year describing the coating of objects with nanocrystalline silver so as to
make them antimicrobrial.
https://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/search-bool.html&r=2&f=G&l=50&co1=AND&d=ptxt&s1=nucryst&OS=nucryst&RS=nucryst
https://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/search-bool.html&r=1&f=G&l=50&co1=AND&d=ptxt&s1=nucryst&OS=nucryst&RS=nucryst