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Insmed Inc INSM

Insmed Incorporated is a global biopharmaceutical company. The Company's first commercial product, ARIKAYCE (amikacin liposome inhalation suspension), is used for the treatment of Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. Its pipeline includes clinical-stage programs, brensocatib and TPIP, as well as other early-stage research programs. Brensocatib is a small molecule, oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP1), which is developing for the treatment of patients with bronchiectasis and other neutrophil-mediated diseases, including chronic rhinosinusitis without nasal polyps (CRSsNP). TPIP is an inhaled formulation of the treprostinil prodrug treprostinil palmitil, which offers a differentiated product profile for pulmonary hypertension associated with interstitial lung disease (PH-ILD) and pulmonary arterial hypertension (PAH).


NDAQ:INSM - Post by User

Bullboard Posts
Post by scissors14on Sep 21, 2004 4:00pm
162 Views
Post# 7946998

Tobin Smith On Insmed

Tobin Smith On InsmedInsmed Incorporated (INSM) is a biopharmaceutical company focused on the discovery and development of drug candidates for the treatment of metabolic diseases and endocrine disorders. The company's approach is to correct metabolic defects in the human body by replacing key regulatory molecules in a physiologically relevant fashion. Insmed has two lead drug candidates, recombinant human (rh) IGF-I/rhIGFBP-3 (also known as SomatoKine), and rhIGFBP-3. Insmed is actively developing these drugs to treat indications in the metabolic and oncology fields. Insmed's SomatoKine drug received orphan drug designation as a treatment for extreme insulin resistance. This is the first step to the FDA approval for ALL diabetes drugs -- that's the promised land. Every biotech firm with a new single molecule drug facing a multibillion-dollar market in phase III trial is valued at over $1 billion - EXCEPT Insmed. With approval of their diabetes drug, we expect 8X - 10X valuation improvement. We are tracking a variety of companies in the diabetes space, and Insmed is one of the most promising speculative names. The idea behind this pick is simple -- they own the intellectual property via patents for a type of hormone replacement therapy that has shown significant impact in controlling diabetes. The market for hormone replacement therapies is huge, with growth hormones representing a billion-dollar market and insulin being a $2 billion-plus sector. Insmed owns the "key" (via dominant patent position) to safely deliver an insulin-like growth factor-binding proteins. Management believes their compound called SomatoKine has a $1 billion annual market potential and could help diabetics reduce their use of insulin -- an exciting prospect for treatment of the disease. It has already been proven effective for diabetes, severe burns and osteoporosis. Those indications are just the tip of the iceberg. This is a great legacy play -- buy under $3 on their third-stage diabetes molecule. Remember our five-year horizon here--we have a $25-$30 stock if our intelligence is right on their diabetes and cancer drugs. This is the way you get rich on stocks like this, using the bottom of the trading range to nibble and then forget about the short term.
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