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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Bullboard Posts
Post by carduon Jan 11, 2005 11:00am
157 Views
Post# 8412943

From the Yahoo board

From the Yahoo boardI believe the second site at St. George Hospital in London was to keep the study on time. This study is independent from the BOD or Oncy researchers. It makes since to keep it on schedule for Marsden's scheduled list of studies. Hopefully we shall hear some news in 22 days. This study is different fron the Glio trials, it has a beginning date and ending date in a facilty that has new trials waiting in the wings. With the large short position closing, it seems to point to a positive NR. I am siding with the bolting shorts on this one. Title: A phase 1 study to evaluate the feasibility, safety and biological effects of administering a wild-type reovirus (REOLYSIN), that selectively replicates in cells expressing activated Ras, intravenously to patients with advanced malignancies. Principal research question: To identify the maximum tolerated dose (MTD) and describe the safety profile of Reolysin. Methodology description: Dose finding (Phase 1/ 2) Sample group description: Total number of RMH patients 40 Outcome measure description: The development of an innovative therapy for the treatment of solid tumours, iwhich can be taken forward in to further phase II and phase III trials. Project web site: https://www.royalmarsden.org/ Research results: Research results are not currently collected by the NRR Project organisation This record refers to a single-centre study Start date: 11 February 2004 End date: 1 February 2005 Project status: Ongoing Contact person: Dr Johann De Bono Section of Medicine Royal Marsden NHS Trust 15, Cotswold Road Sutton Surrey SM2 5NG England Telephone: 020 8643 8901 Fax: 020 7808 2048 E-mail: johann.de-bono@icr.ac.uk
Bullboard Posts