Antibe Therapeutics Inc(Pre-Merger) ATBPF

Can they bring Otenaproxesul to market?

[Bookworm28]

I apologize for asking the question, but I've emailed ATE's Investor Relations numerous times over the last year, and they haven't replied. So I'll ask...

Can the company link an H2S molecule onto someone else's NSAID (e.g. Aleve), and sell the resulting product? I know it must sound ridiculous, but like I said, the company isn't replying to my emails. Reading up on patents, and the law appears to state that if the resulting compound does not share any of the original characteristics of the original two compounds, that's acceptable. In the case of Otenaproxesul, you're obviously wanting the pain killing properties of Aleve to persist - No?

I'm no patent expert. I'm just having a hard time with the idea of tagging an H2S molecule onto someone else's NSAID, and calling it your own. I can't imagine Nuance putting up $20MM if this wasn't do-able.

I'd like to buy, and don't mind waiting, but this is a pretty basic question I'd like to get answered before I jump in.

Thanks

[Forestview]

the patents to the drugs have ended.  Hence them adding the H2S.  So, it's legitimate.  

[MrMugsy]

Exactly - and generic drugs like Naproxen attached to a hydrogen sulfide releading component will create a new molecule that can be protected. We are using ... Naproxen for OTENA (ATB-346) Ketoprofin for ATB-352 Aspirin for ATB-340 Mesalimine for the new IBD drug (and the old ATB-429/428 drugs) Hoping that we're using Rivatigmine for a future AD/PD drug.

[Pragmatist]

  I have looked into ATE's patents as I was curious what they entailed.  This is what I came up with, at least as far as I understand them. For what it's worth.   Antibe's patents are based on three components: a base drug, an H2S releasing compound and (to a lesser extent) a medical indication (eg, OA).  It takes an off-patent drug (NSAIDS to date) and

[Bookworm28]

Thanks for the info Pragmatist. The net can be a real pain at times when doing DD. Found one link that looked pretty legit, but they said Naproxen was under patent until March 2026. Another that said it wasn't under patent. Given the age of Naproxen, your comments, Nuance's investment, I'm thinkin' ATE is fine when it comes to IP considerations. I'd like to have received an

[Pragmatist]

US4803079A - Controlled release naproxen and naproxen sodium tablets - Google Patents Ref says the patent expired approx 15 years ago.  I buy my naproxen from a local pharmacy under the generic name " Naproxen".  I find this to be cheaper than the brand names.

[WalkOverTheStrt]

email [e-mail]  and if she doesnt respond in a week follow up... she does respond.